Green Bioactives

Natural products derived from plants are vital to many industries but sourcing these ingredients economically and sustainably is routinely a significant challenge. Edinburgh-based Green Bioactives Ltd (GBL) is pioneering an innovative plant cell culture approach to the discovery, development, and production of high-value natural plant products that promises to be an ideal solution to these problems

Professor Gary Loake from the University of Edinburgh recognised this unmet need while at the Institute for Molecular Plant Sciences and the Centre for Engineering Biology. Appreciating the potential of his technology, companies began approaching Professor Loake and in response he founded GBL in order to begin the commercialisation of this platform technology.

2018

Start Date

Edinburgh

Location

15

Employees

£650k

Grants

£3M

Investment

The Journey

Appreciating the potential of his technology, companies began approaching Professor Loake and in response he founded GBL in order to begin the commercialisation of this platform technology. An ICURe workshop in Bristol and a subsequent pitch at the Institute of Directors in London resulted in £180K funding from IUK, together with additional investment from friends and family and a business loan, this collectively provided the wherewithal for GBL to start-up at the Roslin Innovation Centre (RIC), a site of excellence for Scottish Biotechnology. Unfortunately, the pandemic then struck, significantly precluding GBL’s travel plans to help drive business development. Fortunately, customers came to GBL, enabling them to demonstrate significant market traction.

 

A pre-seed investment raise from HNW individuals in early 2022 enabled the extension of their funding “runway” which helped them complete their Seed Round investment raise of ~£3M from local and overseas investors in late 2022. This subsequently primed their move to the Pentland Science Park (PSP), just 300M down the road from the RIC, keeping GBL within the Midlothian Science Zone. At PSP GBL were able to build their R and D capacity and expand their team, including key C-suite hires. This R and D expansion supported the generation of key patent applications, the development of their own in-house products and the co-development of other products with multinational companies. In early 2024 their first in-house product entered the market. Founder and CSO Professor Gary Loake said “it has been both a pleasure and privilege to help our highly talented team build GBL”. David McElroy, CEO of GBL said “Our vision is now to become the world’s leading supplier of plant cell culture-derived natural products.”

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    What companies had to say about the Innovate UK ICURe programme?

    2018

    ICURe Workshop

    2018

    University of Edinburgh Innovation Cup

    2019

    Green Bioactives Incorporated

    2019

    ICURe Follow on Funding

    2020

    IBioIC Innovation Grant

    2022

    Pre-seed funding round £90K

    2022

    Seed Round Funding £3M

    2022

    Innovation Voucher SHEFC

    2023

    IUK Engineering Biology Grant

    2023

    Advanced Innovation Voucher

    2023

    UK Patent granted 2590624

    2024

    First product sales

    2024

    SMART: Scotland Grant

    Future Goals

    On the innovation side, GBL’s goals moving forward are to further develop our R and D position in the plant cell culture space developing technologies that will support our biomanufacturing platform. It will also be important to file associated patents where appropriate to protect our IP position. On the sales front GBL will be looking to further develop awareness of the GBL brand, as evidenced by increased sales and business development activities

     

    In addition, GBL plans to introduce more in-house developed products onto the market from their product pipeline and expand their global reach to facilitate business development in additional geographies. GBL will also be working to further scale-up production processes to help meet customer needs. It will also be important for GBL to complete their Pre-Series A round hiring plans, further expanding their team, especially within the production space. It is therefore going to be another busy and exciting year at GBL as they move forward to become the world’s leading supplier of plant cell culture-derived natural products.